Cytokines A group of substances that assist with regulation of immunity and inflammatory responses in the body. Two common forms of cytokines in colostrum are interleukins 1 and 6. They help to regulate the intensity and duration of the immune response and control the communication between the immune system cells while at the same time boosting T lymphocyte activity. Proline Rich Polypeptides (PRP’s) These have been shown to enhance immunity by stimulating a weak immune system and/or balancing an overactive one. This can be done partly by the action of regulating the activity of the thymus gland which is often described as the ‘command centre’ for the immune system. Antibacterial Enzymes These work synergistically with each other and increase antibacterial activity in the presence of lactoferrin, forming a deadly combination against invading bacteria. Lactalbumin; Research has indicated that this substance may have possibilities for enhancement of the immune response against numerous forms of viruses and cancers, including breast and liver. Lactalbumin has also been shown in vulnerable subjects, to raise brain serotonin activity, reduce cortisol concentration and improve moods when under stress. Growth Factors Growth factors found in colostrum include Epidermal Growth Factor (EGF), Trophoblast Growth Factor (TGF), Insulin-like Growth Factor (IGF) and Fibroplast Growth Factor (FGF). Their function primarily, is in the growth, development, and maturation of cells, organs, nerves, muscle and tissues. Growth factors also play a part in the body’s healing and recovery processes. Colostrum versus Immune Milk A recent comparative study was conducted in collaboration with the Otago University Department of Microbiology. In this study, the antibody specificity of a hyperimmune milk product was compared with that of a colostrum product derived from non-immunised, pasture-fed New Zealand cows. Specific antibody titres (concentration) to a panel of 19 of the same 22 pathogenic bacteria and yeast that were used as immunising antigens were determined by enzyme-linked immunoassay (ELISA). Three of the pathogens used as immunising antigens were not available due to regulatory import restraints from the Ministry of Agriculture and Fisheries (MAF). The colostrum demonstrated a significantly higher IgG and IgG1 antibody titre against all of the antigens tested than the hyperimmune milk. In addition, colostrum was shown to stimulate the accumulation of immune cells in the peritoneum of mice. Colostrum was found to contain specific antibodies to the following microbes. BACK
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